Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/21/21 9:00 AM | 9/21/21 8:30 AM | Caykur Rizespor | Altay SK | 1-2 | 1 - 3 points |
| 9/21/21 9:00 AM | 9/21/21 8:30 AM | Fatih Karagümrük | Antalyaspor | 0-0 | 1 - 3 points |
| 9/21/21 12:00 PM | 9/21/21 11:30 AM | Besiktas Istanbul | Adana Demirspor | 3-3 | 1 - 3 points |
| 9/21/21 12:00 PM | 9/21/21 11:30 AM | Yeni Malatyaspor | Sivasspor | 0-1 | 1 - 3 points |
| 9/22/21 9:00 AM | 9/22/21 8:30 AM | Gazisehir Gaziantep FK | Istanbul Basaksehir FK | 1-0 | 1 - 3 points |
| 9/22/21 12:00 PM | 9/22/21 11:30 AM | Göztepe Izmir | Hatayspor | 0-2 | 1 - 3 points |
| 9/22/21 12:00 PM | 9/22/21 11:30 AM | Kayserispor | Galatasaray Istanbul | 3-0 | 1 - 3 points |
| 9/23/21 9:00 AM | 9/23/21 8:30 AM | Konyaspor | Trabzonspor | 2-2 | 1 - 3 points |
| 9/23/21 12:00 PM | 9/23/21 11:30 AM | Fenerbahce Istanbul | Giresunspor | 2-1 | 1 - 3 points |
| 9/23/21 12:00 PM | 9/23/21 11:30 AM | Alanyaspor | Kasimpasa Istanbul | 2-0 | 1 - 3 points |