Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/24/21 12:00 PM | 9/24/21 11:30 AM | Altay SK | Besiktas Istanbul | 2-1 | 1 - 3 points |
| 9/25/21 5:30 AM | 9/25/21 5:00 AM | Sivasspor | Fatih Karagümrük | 4-0 | 1 - 3 points |
| 9/25/21 8:00 AM | 9/25/21 7:30 AM | Antalyaspor | Yeni Malatyaspor | 1-0 | 1 - 3 points |
| 9/25/21 11:00 AM | 9/25/21 10:30 AM | Adana Demirspor | Gazisehir Gaziantep FK | 4-0 | 1 - 3 points |
| 9/26/21 5:30 AM | 9/26/21 5:00 AM | Giresunspor | Kayserispor | 1-1 | 1 - 3 points |
| 9/26/21 8:00 AM | 9/26/21 7:30 AM | Istanbul Basaksehir FK | Caykur Rizespor | 3-0 | 1 - 3 points |
| 9/26/21 8:00 AM | 9/26/21 7:30 AM | Hatayspor | Fenerbahce Istanbul | 1-2 | 1 - 3 points |
| 9/26/21 11:00 AM | 9/26/21 10:30 AM | Galatasaray Istanbul | Göztepe Izmir | 2-1 | 1 - 3 points |
| 9/27/21 12:00 PM | 9/27/21 11:30 AM | Trabzonspor | Alanyaspor | 1-1 | 1 - 3 points |
| 9/27/21 12:00 PM | 9/27/21 11:30 AM | Kasimpasa Istanbul | Konyaspor | 2-2 | 1 - 3 points |