| Date | Home | Away | Result |
|---|---|---|---|
| 4/4/25 8:00 PM | Queretaro F.C. | Club Leon | 1-1 |
| 4/4/25 10:00 PM | Club Tijuana | CID Necaxa | 1-2 |
| 4/4/25 10:05 PM | Puebla FC | Tigres de UANL | 0-0 |
| 4/5/25 6:00 PM | CF Pachuca | CF America | 1-0 |
| 4/5/25 6:00 PM | Atlas Guadalajara | FC Juarez | 1-1 |
| 4/5/25 8:00 PM | San Luis | Mazatlan FC | 2-1 |
| 4/5/25 8:05 PM | CF Monterrey | Deportivo Guadalajara | 3-1 |
| 4/5/25 10:10 PM | CD Cruz Azul | UNAM Pumas | 3-2 |
| 4/6/25 7:00 PM | Deportivo Toluca | Santos Laguna | 0-0 |