| Date | Home | Away | Result |
|---|---|---|---|
| 3/17/19 12:00 PM | KV Kortrijk | Royal Antwerp FC | 2-0 |
| 3/17/19 12:00 PM | SV Zulte-Waregem | KRC Genk | 3-3 |
| 3/17/19 12:00 PM | Standard Liège | Waasland-Beveren | 4-3 |
| 3/17/19 12:00 PM | KV Oostende | RSC Anderlecht | 0-2 |
| 3/17/19 12:00 PM | Sporting Charleroi | KAS Eupen | 1-2 |
| 3/17/19 12:00 PM | Sint-Truidense VV | KAA Gent | 0-2 |
| 3/17/19 12:00 PM | Club Brugge | Royal Excel Mouscron | 1-2 |
| 3/17/19 12:00 PM | KSC Lokeren OV | KSV Cercle Brügge | 3-1 |