Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/13/21 11:00 AM | 8/13/21 11:00 AM | SV Lippstadt 08 | SC Wiedenbrück | 1-0 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | SC Fortuna Köln | FC Wegberg-Beeck | 2-0 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | VfB Homberg | Bor. Mönchengladbach II | 0-2 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | Bonner SC | Rot-Weiss Essen | 0-3 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | Wuppertaler SV | SV Rödinghausen | 2-0 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | Rot-Weiss Oberhausen | KFC Uerdingen | 6-0 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | Preußen Münster | Alemannia Aachen | 2-1 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | Fortuna Düsseldorf II | Sportfreunde Lotte | 2-1 | 5 - 7 points |
| 8/14/21 7:00 AM | 8/14/21 7:00 AM | SV Straelen | Rot-Weiss Ahlen | 3-2 | 5 - 7 points |
| 8/15/21 8:00 AM | 8/15/21 8:00 AM | FC Schalke 04 II | 1. FC Köln II | 1-2 | 5 - 7 points |