Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 2/11/22 12:30 PM | 2/11/22 12:30 PM | SC Fortuna Köln | Wuppertaler SV | 1-0 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | Preußen Münster | Rot-Weiss Ahlen | 2-0 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | Fortuna Düsseldorf II | SV Straelen | 0-4 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | VfB Homberg | Rot-Weiss Essen | 0-1 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | SC Wiedenbrück | Alemannia Aachen | 1-1 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | KFC Uerdingen | Bor. Mönchengladbach II | 1-4 | 5 - 7 points |
| 2/12/22 7:00 AM | 2/12/22 7:00 AM | Bonner SC | 1. FC Köln II | 1-3 | 5 - 7 points |
| 2/13/22 7:00 AM | 2/13/22 7:00 AM | FC Schalke 04 II | SV Rödinghausen | 0-0 | 5 - 7 points |
| 3/9/22 11:00 AM | 3/9/22 11:00 AM | SV Lippstadt 08 | FC Wegberg-Beeck | 0-0 | 5 - 7 points |
| 3/30/22 12:30 PM | 3/30/22 12:30 PM | Rot-Weiss Oberhausen | Sportfreunde Lotte | 1-0 | 5 - 7 points |