Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/11/22 12:00 PM | 3/11/22 12:00 PM | SC Wiedenbrück | SV Rödinghausen | 1-2 | 5 - 7 points |
| 3/12/22 7:00 AM | 3/12/22 7:00 AM | Alemannia Aachen | Sportfreunde Lotte | 1-0 | 5 - 7 points |
| 3/12/22 7:00 AM | 3/12/22 7:00 AM | VfB Homberg | Fortuna Düsseldorf II | 0-2 | 5 - 7 points |
| 3/12/22 7:00 AM | 3/12/22 7:00 AM | SV Lippstadt 08 | SV Straelen | 1-2 | 5 - 7 points |
| 3/12/22 7:00 AM | 3/12/22 7:00 AM | KFC Uerdingen | Rot-Weiss Ahlen | 1-1 | 5 - 7 points |
| 3/12/22 7:00 AM | 3/12/22 7:00 AM | 1. FC Köln II | FC Wegberg-Beeck | 4-1 | 5 - 7 points |
| 3/12/22 7:15 AM | 3/12/22 7:15 AM | Bonner SC | Bor. Mönchengladbach II | 1-1 | 5 - 7 points |
| 3/13/22 8:00 AM | 3/13/22 8:00 AM | FC Schalke 04 II | Wuppertaler SV | 0-4 | 5 - 7 points |
| 4/5/22 12:30 PM | 4/5/22 12:30 PM | Rot-Weiss Oberhausen | Rot-Weiss Essen | 1-1 | 5 - 7 points |
| 4/19/22 12:00 PM | 4/19/22 12:00 PM | Preußen Münster | SC Fortuna Köln | 1-0 | 5 - 7 points |