Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/5/22 12:00 PM | 8/5/22 12:00 PM | SC Fortuna Köln | SV Rödinghausen | 0-2 | 5 - 7 points |
| 8/5/22 12:00 PM | 8/5/22 12:00 PM | Fortuna Düsseldorf II | Alemannia Aachen | 1-1 | 5 - 7 points |
| 8/5/22 12:30 PM | 8/5/22 12:30 PM | Preußen Münster | 1. FC Bocholt | 5-0 | 5 - 7 points |
| 8/6/22 7:00 AM | 8/6/22 7:00 AM | Wuppertaler SV | SC Wiedenbrück | 2-2 | 5 - 7 points |
| 8/6/22 7:00 AM | 8/6/22 7:00 AM | 1. FC Düren | Bor. Mönchengladbach II | 1-0 | 5 - 7 points |
| 8/6/22 7:00 AM | 8/6/22 7:00 AM | Rot-Weiss Ahlen | SG Wattenscheid 09 | 8-0 | 5 - 7 points |
| 8/6/22 7:00 AM | 8/6/22 7:00 AM | Rot-Weiss Oberhausen | SV Straelen | 2-1 | 5 - 7 points |
| 8/7/22 7:00 AM | 8/7/22 7:00 AM | FC Schalke 04 II | SV Lippstadt 08 | 1-3 | 5 - 7 points |
| 8/7/22 7:00 AM | 8/7/22 7:00 AM | 1. FC Kaan-Marienborn | 1. FC Köln II | 1-1 | 5 - 7 points |