Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 5/6/22 12:30 PM | 5/6/22 12:30 PM | SC Wiedenbrück | Preußen Münster | 0-0 | 5 - 7 points |
| 5/6/22 12:30 PM | 5/6/22 12:30 PM | Alemannia Aachen | Fortuna Düsseldorf II | 3-1 | 5 - 7 points |
| 5/7/22 5:00 AM | 5/7/22 5:00 AM | 1. FC Köln II | VfB Homberg | 2-1 | 5 - 7 points |
| 5/7/22 7:00 AM | 5/7/22 7:00 AM | Rot-Weiss Oberhausen | SV Lippstadt 08 | 0-1 | 5 - 7 points |
| 5/7/22 7:00 AM | 5/7/22 7:00 AM | SV Rödinghausen | Rot-Weiss Essen | 0-3 | 5 - 7 points |
| 5/7/22 7:00 AM | 5/7/22 7:00 AM | Rot-Weiss Ahlen | Bonner SC | 1-1 | 5 - 7 points |
| 5/7/22 7:00 AM | 5/7/22 7:00 AM | Bor. Mönchengladbach II | SC Fortuna Köln | 0-4 | 5 - 7 points |
| 5/7/22 7:00 AM | 5/7/22 7:00 AM | FC Wegberg-Beeck | SV Straelen | 2-3 | 5 - 7 points |
| 5/7/22 11:00 AM | 5/7/22 11:00 AM | KFC Uerdingen | FC Schalke 04 II | 3-4 | 5 - 7 points |
| 5/8/22 7:00 AM | 5/8/22 7:00 AM | Sportfreunde Lotte | Wuppertaler SV | 2-1 | 5 - 7 points |