| Date | Home | Away | Result |
|---|---|---|---|
| 5/11/18 2:30 PM | Desportivo Aves | GD Chaves | 2-3 |
| 5/12/18 10:00 AM | Vitoria Guimaraes | FC Porto | 0-1 |
| 5/12/18 2:00 PM | Boavista Porto | Belenenses Lisbon | 1-0 |
| 5/13/18 12:00 PM | Portimonense | FC Pacos de Ferreira | 3-1 |
| 5/13/18 12:00 PM | Rio Ave FC | Sporting Braga | 1-0 |
| 5/13/18 12:00 PM | CD Feirense | Estoril Praia | 0-0 |
| 5/13/18 12:00 PM | Vitoria Setubal | CD Tondela | 1-0 |
| 5/13/18 12:00 PM | Benfica Lisbon | Moreirense FC | 1-0 |
| 5/13/18 12:00 PM | Maritimo Funchal | Sporting Lisbon | 2-1 |