| Date | Home | Away | Result |
|---|---|---|---|
| 11/28/18 5:00 PM | CD San Luis Quillota | Everton | 1-2 |
| 11/29/18 5:30 PM | O'Higgins | Audax Italiano | 4-0 |
| 11/29/18 5:30 PM | Unión Española | Unión La Calera | 1-1 |
| 12/2/18 9:00 AM | Iquique | CD Antofagasta | 0-2 |
| 12/2/18 2:30 PM | Deportes Temuco | Universidad Católica | 1-2 |
| 12/2/18 2:30 PM | Curico Unido | Universidad de Chile | 1-2 |
| 12/2/18 2:30 PM | Palestino | Huachipato | 3-0 |
| 12/2/18 2:30 PM | Colo-Colo | Universidad de Concepcion | 0-2 |