| Date | Home | Away | Result |
|---|---|---|---|
| 5/18/18 1:30 PM | Frosinone Calcio | US Foggia | 2-2 |
| 5/18/18 1:30 PM | Novara Calcio | Virtus Entella | 0-1 |
| 5/18/18 1:30 PM | SSC Bari | Carpi FC | 2-0 |
| 5/18/18 1:30 PM | FC Venice | Pescara Calcio | 0-0 |
| 5/18/18 1:30 PM | US Salernitana | US Palermo | 0-2 |
| 5/18/18 1:30 PM | Spezia Calcio | Parma Calcio 1913 | 0-2 |
| 5/18/18 1:30 PM | FC Empoli | AC Perugia | 2-1 |
| 5/18/18 1:30 PM | FC Cesena | US Cremonese | 1-0 |
| 5/18/18 1:30 PM | AS Cittadella | FC Pro Vercelli | 2-0 |
| 5/18/18 1:30 PM | Ternana Calcio | US Avellino | 1-2 |
| 5/18/18 1:30 PM | Ascoli Calcio | Brescia Calcio | 0-0 |