| Date | Home | Away | Result |
|---|---|---|---|
| 5/14/16 10:00 AM | Juventus Turin | Sampdoria Genua | 5-0 |
| 5/14/16 1:45 PM | SSC Napoli | Frosinone Calcio | 4-0 |
| 5/14/16 1:45 PM | AC Milan | AS Roma | 1-3 |
| 5/14/16 1:45 PM | Sassuolo Calcio | Inter Milan | 3-1 |
| 5/15/16 11:00 AM | AC Chievo Verona | FC Bologna | 0-0 |
| 5/15/16 11:00 AM | FC Empoli | FC Turin | 2-1 |
| 5/15/16 11:00 AM | FC Genua 1893 | Atalanta Bergamo | 1-2 |
| 5/15/16 1:45 PM | Udinese Calcio | Carpi FC | 1-2 |
| 5/15/16 1:45 PM | US Palermo | Hellas Verona | 3-2 |
| 5/15/16 1:45 PM | Lazio Rom | Fiorentina | 2-4 |