| Date | Home | Away | Result |
|---|---|---|---|
| 5/14/17 7:30 AM | Go Ahead Eagles Deventer | Sparta Rotterdam | 1-3 |
| 5/14/17 7:30 AM | AZ Alkmaar | FC Utrecht | 2-3 |
| 5/14/17 7:30 AM | SC Heerenveen | NEC Nijmwegen | 0-2 |
| 5/14/17 7:30 AM | Vitesse Arnheim | Roda JC Kerkrade | 3-0 |
| 5/14/17 7:30 AM | FC Twente Enschede | FC Groningen | 3-5 |
| 5/14/17 7:30 AM | Willem II Tilburg | Ajax Amsterdam | 1-3 |
| 5/14/17 7:30 AM | ADO Den Haag | Excelsior Rotterdam | 4-1 |
| 5/14/17 7:30 AM | PSV Eindhoven | PEC Zwolle | 4-1 |
| 5/14/17 7:30 AM | Feyenoord Rotterdam | Heracles Almelo | 3-1 |