| Date | Home | Away | Result |
|---|---|---|---|
| 5/15/19 12:30 PM | ADO Den Haag | Willem II Tilburg | 6-2 |
| 5/15/19 12:30 PM | VVV Venlo | Vitesse Arnheim | 1-3 |
| 5/15/19 12:30 PM | FC Utrecht | SC Heerenveen | 3-1 |
| 5/15/19 12:30 PM | NAC Breda | PEC Zwolle | 0-0 |
| 5/15/19 12:30 PM | PSV Eindhoven | Heracles Almelo | 3-1 |
| 5/15/19 12:30 PM | FC Emmen | FC Groningen | 1-0 |
| 5/15/19 12:30 PM | Excelsior Rotterdam | AZ Alkmaar | 4-2 |
| 5/15/19 12:30 PM | De Graafschap Doetinchem | Ajax Amsterdam | 1-4 |
| 5/15/19 12:30 PM | Fortuna Sittard | Feyenoord Rotterdam | 1-4 |