| Date | Home | Away | Result |
|---|---|---|---|
| 5/8/16 7:30 AM | FC Utrecht | AZ Alkmaar | 1-3 |
| 5/8/16 7:30 AM | Feyenoord Rotterdam | NEC Nijmwegen | 1-0 |
| 5/8/16 7:30 AM | PEC Zwolle | PSV Eindhoven | 1-3 |
| 5/8/16 7:30 AM | De Graafschap Doetinchem | Ajax Amsterdam | 1-1 |
| 5/8/16 7:30 AM | FC Twente Enschede | Vitesse Arnheim | 2-2 |
| 5/8/16 7:30 AM | Roda JC Kerkrade | Willem II Tilburg | 2-3 |
| 5/8/16 7:30 AM | FC Groningen | Heracles Almelo | 2-1 |
| 5/8/16 7:30 AM | Cambuur-Leeuwarden | Excelsior Rotterdam | 0-2 |
| 5/8/16 7:30 AM | ADO Den Haag | SC Heerenveen | 1-1 |