| Date | Home | Away | Result |
|---|---|---|---|
| 5/13/16 1:30 PM | FC Valencia | Real Sociedad | 0-1 |
| 5/14/16 10:00 AM | Deportivo La Coruna | Real Madrid | 0-2 |
| 5/14/16 10:00 AM | FC Granada | FC Barcelona | 0-3 |
| 5/14/16 12:30 PM | Athletic Bilbao | FC Sevilla | 3-1 |
| 5/14/16 12:30 PM | Atletico Madrid | Celta Vigo | 2-0 |
| 5/15/16 5:00 AM | FC Malaga | UD Las Palmas | 4-1 |
| 5/15/16 12:00 PM | Espanyol Barcelona | SD Eibar | 4-2 |
| 5/15/16 12:30 PM | Rayo Vallecano | UD Levante | 3-1 |
| 5/15/16 12:30 PM | Sporting Gijon | FC Villarreal | 2-0 |
| 5/15/16 12:30 PM | Real Betis Sevilla | FC Getafe | 2-1 |